[Analysis of risk factors for cerebrovascular complications after carotid endarterectomy]
1Department of Vascular Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
Insights
Systolic blood pressure before carotid artery clamping and stump pressure to basic systolic blood pressure index (SSI) > 0.25 are key risk factors for cerebrovascular complications after carotid endarterectomy (CEA). Monitoring these can improve patient outcomes.
Area of Science:
- Vascular Surgery
- Neurology
- Cardiology
Background:
- Carotid endarterectomy (CEA) is a crucial procedure for treating ischemic stroke caused by atherosclerotic carotid artery stenosis.
- Identifying risk factors for cerebrovascular complications post-CEA is essential for improving surgical outcomes and patient safety.
Purpose of the Study:
- To evaluate the risk factors associated with cerebrovascular complications following carotid endarterectomy (CEA).
- To enhance the effectiveness of CEA in managing ischemic stroke patients.
Main Methods:
- Retrospective analysis of clinical data from 295 patients who underwent CEA for atherosclerotic carotid artery stenosis.
- Utilized logistic regression analysis to identify single-factor and multi-factor independent risk factors for postoperative cerebrovascular complications.
Main Results:
- Single-factor analysis identified severe lower limb artery stenosis, pre-clamping systolic and diastolic blood pressure, stump pressure, and post-operative diastolic blood pressure as influencing factors.
- Multi-factor analysis revealed that diastolic blood pressure before carotid artery clamping and a stump pressure to basic systolic blood pressure index (SSI) > 0.25 were independent risk factors for postoperative cerebrovascular complications.
Conclusions:
- Systolic blood pressure before carotid artery clamping and SSI > 0.25 are independent risk factors for post-CEA cerebrovascular complications.
- Close patient follow-up and appropriate medical management post-CEA may help reduce the incidence of these complications and subsequent carotid artery restenosis.
Abstract:
Objective: To evaluate the related risk factors of cerebrovascular complications after carotid endarterectomy (CEA) and to improve the efficacy of CEA in the treatment of ischemic stroke. Methods: The clinical data of 295 patients with atherosclerotic carotid artery stenosis who underwent CEA in the Department of Vascular Surgery, Beijing Anzhen Hospital, Capital Medical University from January 2013 to March 2017 were retrospectively analyzed. Results: As the results of the single-factor analysis of logistics, severe lower limb artery stenosis (RR=5.667, P=0.017), systolic blood pressure before the carotid artery clamping (RR=6.659, P=0.010), diastolic blood pressure before the carotid artery clamping (RR=3.981, P=0.046), stump pressure (RR=5.359, P=0.021), diastolic blood pressure after surgery (RR=9.550, P=0.002), diastolic blood pressure of the first day after surgery (RR=7.932, P=0.005) were influencing factors of postoperative cerebrovascular complications after CEA. The results of multi-factor analysis of logistic regression indicated that diastolic blood pressure before the carotid artery clamping (RR=0.953, P=0.024) and stump pressure to basic systolic blood pressure index (SSI)>0.25 (RR=0.086, P=0.049) were independent risk factors for postoperative cerebrovascular complications after CEA. Conclusion: Systolic blood pressure before carotid artery clamping and SSI>0.25 are independent risk factors for postoperative cerebrovascular complications after CEA. Close follow-up and drug treatment for patients after CEA might be beneficial to reduce postoperative carotid artery restenosis.
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