Association between general and central adiposity and development of hypertension in early childhood

Maira A Ortiz-Pinto1,2,3, Honorato Ortiz-Marrón4, Isabel Ferriz-Vidal5

  • 11 Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Spain.

Insights

Childhood obesity, both general and abdominal, is linked to increased high blood pressure risk. Maintaining a healthy weight by age 6 mitigates this risk, highlighting the importance of weight management in early childhood.

Area of Science:

  • Pediatrics
  • Cardiovascular Health
  • Public Health

Background:

  • Childhood obesity is a growing public health concern with potential long-term health implications.
  • High blood pressure (hypertension) in childhood is increasingly recognized and associated with adult cardiovascular disease.
  • Early identification and intervention for risk factors like obesity are crucial for preventing future health issues.

Purpose of the Study:

  • To investigate the association between general and abdominal obesity in 4-year-old children and the development of high blood pressure by age 6.
  • To analyze the impact of incident and persistent excess weight on blood pressure in early childhood.
  • To determine if weight remission affects the risk of developing high blood pressure.

Main Methods:

  • A longitudinal study of 1796 Spanish children, followed from age 4 to 6 years.
  • Measurements included blood pressure, body mass index (BMI), and waist circumference.
  • Statistical analyses employed linear and logistic regressions, adjusting for relevant covariates.

Main Results:

  • Children with general or abdominal obesity at age 4 showed increased systolic (4-5 mmHg) and diastolic (2.5-3 mmHg) blood pressure by age 6.
  • Incident and persistent excess weight (BMI) were associated with significantly higher odds of high blood pressure (OR 2.49 and 2.54, respectively).
  • Abdominal obesity also showed increased odds for incident (OR 2.81) and persistent (OR 3.42) high blood pressure, with similar trends for waist-height ratio.

Conclusions:

  • Persistent or new-onset excess weight (BMI) and abdominal obesity in early childhood are associated with an increased risk of high blood pressure.
  • Children who achieved normal weight after initial excess weight did not show an elevated risk for high blood pressure.
  • These findings underscore the importance of addressing childhood obesity to prevent hypertension and cardiovascular complications later in life.
Abstract

Related Concept Videos

Erikson's Theory on Socioemotional Development during Childhood01:28

Erikson's Theory on Socioemotional Development during Childhood

Erik Erikson, a stage theorist, adapted Freud's theory to emphasize social factors in personality development throughout life, a concept known as psychosocial development. Unlike Freud, who focused on early childhood, Erikson believed that personality evolves across eight life stages, each marked by a specific challenge or "crisis." Successful resolution of each stage fosters competence, while failure may lead to feelings of inadequacy.
The first four of Erikson's eight...
1.0K
Piaget's Theory of Cognitive Development from Childhood into Adulthood01:25

Piaget's Theory of Cognitive Development from Childhood into Adulthood

Jean Piaget's theory of cognitive development emphasizes the role of thinking in a child's learning process, suggesting that children are naturally curious about their environment. His approach to development is discontinuous, proposing that cognitive abilities progress through distinct stages, each with unique characteristics. Central to Piaget's theory is schemata—mental structures that allow individuals to understand and interpret the world.
Schemata: Building Blocks of Knowledge
1.5K
The Central Dogma01:25

The Central Dogma

Overview
139.1K
Measures of Central Tendency02:16

Measures of Central Tendency

The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians,...
20.2K
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.1K
Associative Learning01:27

Associative Learning

Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.3K