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Association between general and central adiposity and development of hypertension in early childhood
Maira A Ortiz-Pinto1,2,3, Honorato Ortiz-Marrón4, Isabel Ferriz-Vidal5
11 Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Spain.
Insights
Childhood obesity, both general and abdominal, is linked to increased high blood pressure risk. Maintaining a healthy weight by age 6 mitigates this risk, highlighting the importance of weight management in early childhood.
Area of Science:
- Pediatrics
- Cardiovascular Health
- Public Health
Background:
- Childhood obesity is a growing public health concern with potential long-term health implications.
- High blood pressure (hypertension) in childhood is increasingly recognized and associated with adult cardiovascular disease.
- Early identification and intervention for risk factors like obesity are crucial for preventing future health issues.
Purpose of the Study:
- To investigate the association between general and abdominal obesity in 4-year-old children and the development of high blood pressure by age 6.
- To analyze the impact of incident and persistent excess weight on blood pressure in early childhood.
- To determine if weight remission affects the risk of developing high blood pressure.
Main Methods:
- A longitudinal study of 1796 Spanish children, followed from age 4 to 6 years.
- Measurements included blood pressure, body mass index (BMI), and waist circumference.
- Statistical analyses employed linear and logistic regressions, adjusting for relevant covariates.
Main Results:
- Children with general or abdominal obesity at age 4 showed increased systolic (4-5 mmHg) and diastolic (2.5-3 mmHg) blood pressure by age 6.
- Incident and persistent excess weight (BMI) were associated with significantly higher odds of high blood pressure (OR 2.49 and 2.54, respectively).
- Abdominal obesity also showed increased odds for incident (OR 2.81) and persistent (OR 3.42) high blood pressure, with similar trends for waist-height ratio.
Conclusions:
- Persistent or new-onset excess weight (BMI) and abdominal obesity in early childhood are associated with an increased risk of high blood pressure.
- Children who achieved normal weight after initial excess weight did not show an elevated risk for high blood pressure.
- These findings underscore the importance of addressing childhood obesity to prevent hypertension and cardiovascular complications later in life.
Objectives:
To evaluate the association of general and abdominal obesity with high blood pressure in young children.
Methods:
A longitudinal study including 1796 participants from the Madrid region (Spain) with baseline at age 4 years and a follow-up 2 years later. Blood pressure, body mass index and waist circumference were measured during a physical examination. We evaluated the association between obesity at baseline and weight changes between the ages of 4 and 6 years and high blood pressure. Data were analysed using linear and logistic regressions adjusted for covariates.
Results:
Obese 4 year olds (general or abdominal obesity) experienced an average 4-5 mmHg increase in systolic blood pressure and a 2.5-3 mmHg increase in diastolic blood pressure by the age of 6 years. Compared to children maintaining a non-excess weight (based on body mass index) during follow-up incident and persistent cases of excess weight (overweight or obesity) had an odds ratio (OR) for high blood pressure of 2.49 (95% confidence interval (CI) 1.50-4.13) and OR 2.54 (95% CI 1.27-5.07), respectively. Regarding abdominal obesity we estimated OR 2.81 (95% CI 0.98-8.02) for incident cases and OR 3.42 (95% CI 1.38-8.49) for persistent cases. Similar estimates for the waist-height ratio were observed. Individuals who experienced remission to non-excess weight did not have an increased risk of high blood pressure.
Conclusions:
We observed an increased risk for high blood pressure among 4-year-olds who presented with persistent or incident cases of excess weight (body mass index) or abdominal obesity after 2 years of follow-up. Children with excess weight or obesity at baseline who remitted to non-excess weight did not exhibit an increased risk of high blood pressure.
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