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Growth hormone-releasing hormone. Studies in cord blood from term human newborns
J Argente1, A Acquafredda, L Cavallo
1INSERM U-188, Hôpital Saint-Vincent-de-Paul, Paris, France.
Biology of the Neonate
|January 1, 1987
Abstract:
Plasma growth hormone-releasing hormone (GHRH) was measured by radioimmunoassay in the cord blood from 32 healthy human newborns after 38-41 weeks of gestation. All were born by uncomplicated vaginal delivery. The GHRH levels in cord blood were 78.33 +/- 8.35 pg/ml at 40 weeks of gestation, approximately threefold higher than the levels at 38 weeks of gestation (27.00 +/- 2.55 pg/ml). No significant differences were found between girls and boys. The rise of plasma GHRH levels in cord blood of the full-term newborns between 38 and 40 weeks of gestation suggests a role of this peptide in the neonatal growth regulation.