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Updated: Jan 23, 2026
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Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues
Published on: March 31, 2016
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Adipose Tissue Composition in Obesity and After Bariatric Surgery
Gian Franco Adami1,2, Federico Carbone3,4, Fabrizio Montecucco3,4
1Department of Internal Medicine, University of Genova, 8, viale Benedetto XV, 16132, Genova, Italy. adami@unige.it.
Obesity Surgery
|June 14, 2019
Summary
Bariatric surgery improves metabolic health by reducing ectopic and epicardial fat. It also increases brown adipose tissue activity, aiding weight loss and long-term benefits.
Area of Science:
- Adipose tissue biology
- Metabolic surgery
- Cardiovascular health
Background:
- Adipose tissue regulates energy balance and inflammation.
- Bariatric surgery impacts adipose tissue composition and activity.
- Epicardial and ectopic fat are linked to metabolic dysfunction.
Purpose of the Study:
- To review changes in adipose tissue after bariatric surgery.
- To focus on epicardial fat, ectopic fat, and white/brown adipose tissue interactions.
- To understand the role of adipose tissue in metabolic recovery and cardiovascular risk reduction post-surgery.
Main Methods:
- Review of existing literature on adipose tissue changes post-bariatric surgery.
- Analysis of studies focusing on epicardial and ectopic fat.
- Examination of the interplay between white and brown adipose tissues.
Main Results:
- Bariatric surgery leads to improved ectopic and epicardial fat profiles.
- These improvements correlate with enhanced metabolic recovery and reduced cardiovascular risk.
- Roux-en-Y gastric bypass and biliopancreatic diversion increase brown adipose tissue size and activity.
Conclusions:
- Post-bariatric surgery adipose tissue changes, particularly reduced ectopic/epicardial fat and increased brown adipose tissue, drive metabolic improvements.
- Increased brown adipose tissue activity may be linked to altered entero-hormonal patterns, such as elevated GLP-1.
- These adaptations contribute to sustained weight loss and improved health outcomes after bariatric procedures.
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