Related Experiment Video
Updated: Jan 23, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
The Current Status of Intervention for Intermediate Coronary Stenosis in the Korean Percutaneous Coronary
Jin Ho Kim1, Woonggil Choi1, Ki Chang Kim1
1Department of Cardiology, Konkuk University School of Medicine, Chungju, Korea.
Insights
Percutaneous coronary intervention (PCI) for intermediate coronary lesions is often guided by intravascular ultrasound (IVUS) over fractional flow reserve (FFR). Increased FFR use for intermediate lesions is recommended to improve PCI appropriateness.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Intermediate coronary lesions (50-70% stenosis) pose challenges in visual estimation, leading to inappropriate stenting or deferred treatment.
- Accurate assessment is crucial for optimal patient outcomes in percutaneous coronary intervention (PCI).
Purpose of the Study:
- To evaluate the current practice patterns of PCI for intermediate coronary lesions in Korea.
- To analyze the utilization of invasive physiologic (FFR) and imaging (IVUS) studies in guiding PCI decisions.
Main Methods:
- Analysis of the Korean PCI (K-PCI) registry data from January 1, 2014, to December 31, 2014.
- Intermediate lesions defined as 50-70% luminal narrowing by visual estimation.
- Comparison of PCI rates based on the performance of invasive physiologic or imaging studies.
Main Results:
- Physiology-guided PCI was performed in 16.8% (LAD), 9.8% (LCX), and 13.2% (RCA) of intermediate lesions.
- Intravascular ultrasound (IVUS) was more frequently used than fractional flow reserve (FFR) for PCI guidance across all major coronary arteries.
- PCI was more common in hospitals with FFR availability, particularly for left main and proximal LAD lesions.
Conclusions:
- Current PCI practices for intermediate lesions show varied use of FFR and IVUS.
- Encouraging more widespread adoption of FFR for intermediate lesions is recommended to optimize treatment strategies.
Background And Objectives:
Intermediate coronary lesion that can be under- or over-estimated by visual estimation frequently results in stenting of functionally nonsignificant lesions or deferral of percutaneous coronary intervention (PCI) of significant lesions inappropriately. We evaluated current status of PCI for intermediate lesions from a standardized database in Korea.
Methods:
We analyzed the Korean percutaneous coronary intervention (K-PCI) registry data which collected a standardized PCI database of the participating hospitals throughout the country from January 1, 2014, through December 31, 2014. Intermediate lesion was defined as a luminal narrowing between 50% and 70% by visual estimation and then compared whether the invasive physiologic or imaging study was performed or not.
Results:
Physiology-guided PCI for intermediate lesions was performed in 16.8% for left anterior descending artery (LAD), 9.8% for left circumflex artery (LCX), 13.2% for right coronary artery (RCA). PCI was more frequently performed using intravascular ultrasound (IVUS) than using fractional flow reserve (FFR) for coronary artery segments (27.7% vs. 13.9% for LAD, 32.9% vs. 8.1% for LCX, and 33.8% vs. 10.8% for RCA). In accordance with or without FFR, PCI for intermediate lesions was more frequently performed in the hospitals with available FFR device than without FFR, especially in left main artery (LM), proximal LAD lesion (40.9% vs. 5.9% for LM, 24.6% vs 7.6% for proximal LAD).
Conclusions:
These data provide the current PCI practice pattern with the use of FFR and IVUS in intermediate lesion. More common use of FFR for intermediate lesion should be encouraged.
More Related Videos
06:39Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
06:39Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
Related Concept Videos
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Heart Failure VII: Nursing Interventions