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Updated: Jan 23, 2026

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Neck pain in episodic migraine: a cross-sectional study
Zhe Yu1, Rongfei Wang1, Ran Ao1
1Department of Neurology, Chinese PLA General Hospital, Beijing 100853, People's Republic of China.
Journal of Pain Research
|June 14, 2019
Summary
Neck pain is common in episodic migraine (EM). This study found higher neck and head muscle tenderness in EM with neck pain, but common lifestyle factors were not associated. Further research is needed.
Area of Science:
- Neurology
- Pain Medicine
- Headache Research
Background:
- Neck pain is more prevalent in episodic migraine (EM) patients compared to the general population.
- Individuals with episodic migraine often exhibit widespread hypersensitivity in the cranio-cervical region.
Purpose of the Study:
- To investigate factors associated with neck pain in episodic migraineurs.
- To compare pericranial muscle tenderness between episodic migraine patients with and without neck pain.
Main Methods:
- Fifty episodic migraine patients with neck pain and 50 age- and sex-matched patients without neck pain were enrolled.
- Headache characteristics, lifestyle factors, migraine disability, and neck disability were assessed.
- Cranio-cervical muscle tenderness and mechanical pain thresholds were evaluated during migraine-free periods.
Main Results:
- No significant differences in headache intensity, disability, duration, or frequency were found between groups.
- Lifestyle factors (smoking, alcohol, coffee, BMI, sleep, screen time) were not associated with neck pain in EM.
- Episodic migraine patients with neck pain showed significantly higher neck and cephalic muscle tenderness scores.
Conclusions:
- Cranio-cervical muscle tenderness differs significantly between episodic migraine patients with and without neck pain.
- The studied lifestyle factors do not appear to be associated with the onset of neck pain in episodic migraine.
- Further research is required to identify other potential factors contributing to neck pain in episodic migraine.
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