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Updated: Jan 23, 2026

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Vasectomy reversal utilizing fibrin glue.

G Luke Machen1, Ali M Mahmoud2, Colin E Kleinguetl1

  • 1Division of Urology, Department of Surgery, Scott and White Medical Center/Texas A&M College of MedicineTempleTexas.

Proceedings (Baylor University. Medical Center)
|June 14, 2019
PubMed
Summary

This study found that a microscopic vasectomy reversal technique using fibrin glue achieved an 88.4% patency rate. Success was particularly notable for reversals performed within 10 years of the original vasectomy.

Keywords:
Fibrin gluemale infertilityvasectomy reversal

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Area of Science:

  • Urology
  • Surgical Techniques

Background:

  • Vasectomy is a common male sterilization procedure with a significant number of reversals performed annually.
  • Traditional vasovasostomy techniques lack clear superiority in success rates.
  • A microscopic technique utilizing fibrin glue for anastomosis reinforcement was previously described.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of a specific microscopic vasectomy reversal technique.
  • To analyze patient demographics and operative characteristics associated with vasovasostomy success.

Main Methods:

  • Retrospective chart review of patients undergoing vasectomy reversal.
  • Application of a microscopic technique with three full-thickness sutures reinforced by fibrin glue.
  • Analysis of demographic data, operative characteristics, and patency rates.

Main Results:

  • Overall vasovasostomy patency rate of 88.4% was achieved.
  • A statistically significant higher success rate was observed for reversals within 10 years of vasectomy (OR 2.91, P=0.048).
  • Median operative time was 94 minutes, suggesting potential cost efficiencies.

Conclusions:

  • The described microscopic vasectomy reversal technique offers acceptable patency rates.
  • The technique is particularly effective for patients with shorter intervals between vasectomy and reversal (≤10 years).
  • Potential cost savings may be realized due to reduced operating room time and suture utilization.