Related Experiment Video
Updated: Jan 23, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Aortic valve endocarditis from Enterococcus hirae infection
Callie Gittemeier Ebeling1, Bryan Tyler Romito1
1Department of Anesthesiology and Pain Management, Division of Critical Care, The University of Texas Southwestern Medical CenterDallasTexas.
This study documents the first U.S. case of human infective endocarditis caused by Enterococcus hirae, a rare bacterial pathogen. This finding expands our understanding of Enterococcus hirae as a potential human disease agent.
Area of Science:
- Medical microbiology
- Infectious diseases
- Cardiology
Background:
- Staphylococci, streptococci, and enterococci are common causes of endocarditis.
- Accurate pathogen identification is crucial for effective endocarditis treatment.
- Enterococcus hirae is infrequently reported as a human pathogen, often associated with avian species.
Observation:
- A rare case of infective endocarditis in a human patient was identified.
- The causative agent was identified as Enterococcus hirae.
- This case occurred in the United States.
Findings:
- This represents the first documented human Enterococcus hirae infective endocarditis case in the USA.
- Globally, this is only the fourth reported case of human infective endocarditis attributed to Enterococcus hirae.
- The study highlights the potential for Enterococcus hirae to cause serious human infections.
Implications:
- Clinicians should consider Enterococcus hirae in the differential diagnosis of endocarditis, especially in specific patient populations.
- Further research is warranted to understand the pathogenicity and transmission of Enterococcus hirae in humans.
- This case underscores the importance of comprehensive microbiological identification in infectious disease management.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis I: Introduction
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Mitral Valve Prolapse I: Introduction

