Microscopic polyangiitis associated with subarachnoid hemorrhage.

Area of Science:

• Nephrology
• Neurology
• Rheumatology

Background:

• Microscopic polyangiitis (MPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis primarily affecting small vessels.
• Aneurysms in medium-sized vessels and subarachnoid hemorrhage (SAH) are rarely reported complications of MPA.

Purpose of the Study:

• To report a rare case of SAH in a patient with MPA.
• To highlight the potential association between MPA and cerebrovascular events like SAH.

Main Methods:

• Case report of an 85-year-old female patient diagnosed with MPA and rapid progressive glomerulonephritis.
• Documentation of the patient's subsequent development of SAH and surgical intervention.

Main Results:

• The patient presented with MPA-induced glomerulonephritis and subsequently developed SAH.
• The co-occurrence of MPA and SAH complicated the patient's condition, underscoring a potential link.

Conclusions:

• Cerebrovascular disease, including SAH, should be considered in patients with MPA.
• Increased physician awareness and investigation of intracranial vessels in MPA patients may improve outcomes.