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Updated: Jan 23, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
How to prepare and manage a systematic review and meta-analysis of clinical studies
James R Berstock1, Michael R Whitehouse2,3
1University of British Colombia Department of Orthopaedics, Gordon & Leslie Diamond Health Care Centre, Vancouver, British Columbia, Canada.
Abstract:
Use the PICO framework to formulate a specific clinical question.Formulate a search strategy.Prospectively register the review protocol.Execute the literature search.Apply eligibility criteria to exclude irrelevant studies.Extract data and appraise each study for risk of bias and external validity.Provide a narrative review.If appropriate data are available, perform a meta-analysis.Report the review findings in the context of the risk of bias assessment, any sensitivity analyses and the analysis of risk of publication bias.Useful resources include the Cochrane Handbook, PROSPERO, GRADE and PRISMA. Cite this article: EFORT Open Rev 2019;4:213-220. DOI: 10.1302/2058-5241.4.180049.
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