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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Mycotic aortic aneurysm due to brucellosis
Abdullah Alhaizaey1, Mohammed Alassiri1, Musaed Alghamdi1
1Division of Vascular Surgery, Aseer Central Hospital, King Khalid University, Abha, Saudi Arabia.
Abstract:
Brucellosis is a multisystem zoonotic disease. Mycotic aneurysm due to Brucella is rare and has no clear management approach. Here, we present two cases of mycotic aortic aneurysm due to Brucella. The first patient was treated with surgical resection of a symptomatic infrarenal abdominal aortic aneurysm combined with lifelong doxycycline and rifampicin. The second patient improved with conservative treatment including a 6-month course of antibiotics and regular clinical and radiologic monitoring. Through these cases, we hope to draw attention to this serious adverse effect of Brucella and the importance of management of its local arterial complications, especially in endemic areas.
Insights
Brucellosis can cause rare aortic aneurysms. Management varies, with one patient treated surgically and another conservatively with antibiotics, highlighting the need for awareness in endemic regions.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Cardiology
Background:
- Brucellosis is a zoonotic disease with systemic effects.
- Mycotic aneurysms, particularly those caused by Brucella, are infrequent and lack standardized treatment protocols.
Observation:
- Two cases of mycotic aortic aneurysm caused by Brucella are presented.
- The first case involved surgical resection of an infrarenal abdominal aortic aneurysm with long-term antibiotic therapy (doxycycline and rifampicin).
- The second case showed improvement with conservative management, including a six-month antibiotic course and ongoing monitoring.
Findings:
- Successful management of Brucella-related mycotic aortic aneurysms can be achieved through both surgical intervention and conservative antibiotic therapy.
- Individualized treatment approaches are crucial given the rarity and varied presentations of these aneurysms.
Implications:
- This study emphasizes the importance of recognizing Brucella as a potential cause of mycotic aneurysms.
- It highlights the need for tailored management strategies for arterial complications of brucellosis, especially in areas where the disease is endemic.
- Increased clinical suspicion and appropriate diagnostic workup are essential for timely intervention.
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