Mycoplasma pneumoniae with para-infectious cerebral complications

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Johanna M Birrell1, Emily Woolnough1, Emma Spencer1

  • 1Royal Darwin Hospital, 105 Rocklands Drive, Tiwi, NT, 0810, Australia.

Respiratory Medicine Case Reports
|June 14, 2019
PubMed

Insights

Mycoplasma pneumoniae infection can cause serious neurological issues like raised intracranial pressure. Early diagnosis using nasopharyngeal PCR is crucial for timely treatment with azithromycin.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Microbiology

Background:

  • Mycoplasma pneumoniae commonly causes mild respiratory illness.
  • Extrapulmonary complications, including neurological manifestations, can occur.
  • Raised intracranial pressure is a rare but serious complication.

Observation:

  • A 33-year-old man presented with headache and elevated intracranial pressure.
  • The patient's symptoms were a para-infectious complication of Mycoplasma pneumoniae infection.
  • Nasopharyngeal PCR confirmed Mycoplasma pneumoniae, while IgM antibodies were initially negative.

Findings:

  • Nasopharyngeal PCR facilitated early diagnosis of Mycoplasma pneumoniae infection.
  • Azithromycin is the recommended treatment for Mycoplasma pneumoniae.
  • Early detection of Mycoplasma pneumoniae is essential for managing neurological complications.

Implications:

  • Integrating Mycoplasma pneumoniae PCR into respiratory viral panels can improve patient outcomes.
  • Early directed therapy enhances antimicrobial stewardship.
  • Recognizing neurological complications of Mycoplasma pneumoniae is vital for clinicians.
Keywords:
Atypical pneumoniaMycoplasma pneumoniaeRaised intracranial pressure

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