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Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study

John F Rebhun1, Qin Du2, Molly Hood1

  • 1Department of Analytical Sciences, Nutrilite Health Institute, Ada, MI, 49355, USA.

Journal of Traditional and Complementary Medicine
|June 14, 2019
PubMed
Abstract

Keywords:
Anti-inflammatoryBMD, bone mineral densityBSA, bovine serum albuminBmp4, bone morphogenic protein 4CRE, cyclic adenosine monophosphate response elementCREB, cyclic adenosine monophosphate response element binding proteinDEXA, dual-energy X-ray absorptiometryDMSO, Dimethyl sulfoxideDrynaria fortuneiE2, estradiolER, estrogen receptorERE, estrogen response elementEpimedium brevicornuEstrogenicFBS, fetal bovine serumFsk, forskolinHprt, hypoxanthine-guanine phosphoribosyl-transferaseIL-1, interleukin 1LBD, ligand binding domainLBM, low bone massM-CSF, macrophage colony-stimulating factorMAPK, mitogen activated protein kinaseNF-κβ, nuclear factor kappa betaOP, osteoporosisOsteoporosisPTH, parathyroid hormonePTHrp, PTH related peptideRANKL, receptor activator of nuclear factor kappa beta ligandRLU, relative luminescence unitROI, region of interestRunx2, runt-related transcription factor 2SFM, serum free mediaTCM, traditional Chinese medicineTNFα, tumor necrosis factor alphaTRAP, tartrate-resistant acid phosphataseUAS, upstream activating sequencecAMP, cyclic adenosine monophosphateqPCR, quantitative polymerase chain reaction

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