Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

3.0K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
3.0K
Induced-fit Model01:13

Induced-fit Model

89.0K
Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
89.0K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

27.3K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
27.3K
Spontaneous and Induced Mutations01:30

Spontaneous and Induced Mutations

2.1K
Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).
2.1K
Induced Electric Dipoles01:28

Induced Electric Dipoles

4.7K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.7K
Induced Electric Fields01:23

Induced Electric Fields

4.6K
The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Successful Ocular Structural Restoration of Aggressive Necrotizing Sclerouveitis Following Pterygium Excision: Infectious, Autoimmune, or Both?

Research square·2026
Same author

Lightweight YOLOv8-based real-time detection of pine wilt disease from drone imagery.

Frontiers in plant science·2026
Same author

Intralenticular Stratification in a Complicated Cataract.

JAMA ophthalmology·2026
Same author

The Impact of Integrated Nursing Interventions on Rehabilitation Outcomes for Children With Severe Pneumonia in the Paediatric Intensive Care Unit: A Meta-Analysis.

Nursing in critical care·2026
Same author

Multiplexed Photo-Cross-Linking Reveals Comprehensive Midnolin Interactome: Insights into Ubiquitin-Independent Degradation and Functional Diversity.

Journal of the American Chemical Society·2026
Same author

Utilization of an automated machine learning approach for the detection of granular corneal dystrophy via slit lamp photographs.

BMC ophthalmology·2025
Same journal

Malignant teratoid medulloepithelioma with retinal invasion masquerading as vasoproliferative retinal tumor in an adult.

American journal of ophthalmology case reports·2026
Same journal

The paradox of treatment: Ciliary effusion induced by travoprost - A case report.

American journal of ophthalmology case reports·2026
Same journal

Orbital Fat Involvement by Metastatic Multiple Myeloma Mimicking Involutional Lower Eyelid Fat Herniation: A Case Report.

American journal of ophthalmology case reports·2026
Same journal

Ultra-widefield optical coherence tomography demonstrates subtle vitreoretinal interface changes driving conversion of retinoschisis to retinal detachment.

American journal of ophthalmology case reports·2026
Same journal

Coats-like exudative vasculopathy in a patient with Bardet-Biedl syndrome.

American journal of ophthalmology case reports·2026
Same journal

Primary intraosseous cavernous hemangioma of the zygomatic bone.

American journal of ophthalmology case reports·2026
See all related articles

Related Experiment Video

Updated: Jan 23, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

9.3K

Bilateral methamphetamine-induced ischemic retinopathy.

Jingli Guo1, Wenyi Tang1, Wei Liu1

  • 1Dept. of Ophthalmology, Eye and ENT Hospital of Fudan University, NHC Key Laboratory of Myopia (Fudan University), Shanghai, China.

American Journal of Ophthalmology Case Reports
|June 14, 2019
PubMed
Summary
This summary is machine-generated.

Methamphetamine abuse can cause severe vision loss due to bilateral ischemic retinopathy, including central retinal vein and branch retinal artery occlusion. Panretinal photocoagulation may help treat this condition.

Keywords:
IntranasalIschemic retinopathyMethamphetamineMultimodal imagingPanretinal photocoagulation

More Related Videos

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
05:20

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

8.1K
Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

30.1K

Related Experiment Videos

Last Updated: Jan 23, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

9.3K
A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
05:20

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

8.1K
Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

30.1K

Area of Science:

  • Ophthalmology
  • Toxicology
  • Neurology

Background:

  • Methamphetamine abuse is a growing public health concern with potential systemic and ocular complications.
  • Ischemic retinopathy, characterized by retinal non-perfusion, can lead to significant vision impairment.

Observation:

  • A 37-year-old male with a history of methamphetamine abuse presented with bilateral vision deterioration.
  • Multimodal imaging revealed bilateral branch retinal artery occlusion and central retinal vein occlusion with vitreous hemorrhage.
  • Systemic evaluation showed ischemic changes in the brain, suggesting widespread vascular compromise.

Findings:

  • The patient was diagnosed with methamphetamine-induced ischemic retinopathy.
  • Fundus fluorescein angiography and OCT angiography demonstrated extensive peripheral retinal non-perfusion and neovascularization.
  • Panretinal photocoagulation (PRP) was administered, leading to improved vision in one eye and resolution of vitreous hemorrhage.

Implications:

  • This case underscores the severe ocular risks associated with methamphetamine abuse, including simultaneous bilateral central retinal vein and branch retinal artery occlusions.
  • Extensive bilateral ischemic retinopathy secondary to methamphetamine abuse has not been previously documented with advanced imaging techniques.
  • Panretinal photocoagulation is a potential treatment option for methamphetamine-induced ischemic retinopathy.