Related Experiment Videos
A case of Shwachman syndrome with increased spontaneous chromosome breakage
1Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Human Genetics
|November 1, 1987
Abstract:
In a patient with Shwachman syndrome, a high incidence of chromosome breakage was found. Chromosome studies done on three occasions on the patient's PHA-stimulated peripheral blood lymphocytes showed elevated frequencies of spontaneous chromosome aberrations compared with those in normal individuals. The patient's lymphocytes did not show increased sensitivity to mitomycin C.