Related Experiment Video
Updated: Jan 23, 2026

Examination of Host Phenotypes in Gambusia affinis Following Antibiotic Treatment
Published on: February 22, 2017
Seeing Is Believing: Vitamin A Promotes Skin Health through a Host-Derived Antibiotic
1Department of Dermatology, University-Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Abstract:
In this issue of Cell Host & Microbe, Harris et al. (2019) show that members of the resistin-like molecule (RELM) family are bactericidal, antimicrobial peptides that promote skin defenses in a vitamin-A-dependent manner. Administration of vitamin A analogs triggers RELM, which improves host resistance against skin pathogens in mice.
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