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Updated: Jan 23, 2026

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
Published on: September 7, 2022
Trial of Heat Inactivation of Selected Viruses Following Irradiation
Eugene C Pirtle1, Terry A Proescholdt1, George W Beran1
1Department of Microbiology, Immunology, and Preventive Medicine, 2180 Veterinary Medicine Complex, Iowa State University, Ames, Iowa 50011, USA.
Abstract:
Four selected viruses were irradiated in ground pork with an electron beam at absorbed doses of 4.4 to 5.27 kG. Irradiated and nonirradiated viruses were heated at four temperatures for four time intervals and assayed for surviving virus. Data were examined for evidence of irradiation-heat interaction to determine whether absorbed irradiation would sensitize virus so that a lesser amount of heat would be required for inactivation. It was determined that irradiation does not increase lability to heat to a level that has practical application in virus inactivation.
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