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Updated: Jan 23, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Melanoma diagnosis: traumatic impact of the event on the patient
Eleonora Campolmi1, Margherita Riccio2, Bernardo Carli2
1Unit of Melanoma and Skin Cancer, Division of Dermatology, Department of Surgery and Translational Medicine, Tuscany Center Health District, University of Florence, Florence, Italy - e.campolmi@gmail.com.
Background:
The aim of our study was to consider the distressing impact of the diagnosis in a group of patients with metastatic melanoma, and the effects it could have on the quality of life of the patients.
Methods:
We proposed an Impact Event Scale (IES-R) to a group of 31 patients. The patients were positive to the distress thermometer (DS) and accepted the psychological support. After six months from the start of the treatment we made a semi-structured interview of 10 multiple choice questions.
Results:
Sixty-five per cent of women and 50% of men report that all the event related to the disease, cause emotions that recall the disease. Eighty-two per cent of women compared to 50% of men, report that the thought of their medical condition tends to affect their quality of sleep; the patients report feelings of anger and irritation (41% of the women and 78% of the men).
Conclusions:
The traumatic aspects following the diagnosis of melanoma burst powerfully into the life of these patients, who show different reactions, also according to gender.
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