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Preventing Rheumatoid Arthritis: A Global Challenge

Jessica Widdifield1

  • 1Sunnybrook Research Institute, Holland Bone & Joint Research Program, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada.

Clinical Therapeutics
|June 15, 2019
PubMed

Insights

Early rheumatoid arthritis (RA) treatment can prevent disease progression. However, global challenges hinder identifying at-risk patients for RA prevention strategies.

Area of Science:

  • Rheumatology and Immunology
  • Preventive Medicine
  • Health Services Research

Background:

  • Significant progress in identifying rheumatoid arthritis (RA) biomarkers, genetic factors, and therapeutic targets.
  • Early RA intervention can alter disease course and potentially achieve remission.
  • Global challenges persist in identifying individuals at risk for RA development.

Purpose of the Study:

  • To review challenges in primary, secondary, and tertiary prevention of RA within healthcare systems.
  • To discuss patient, provider, and system-level barriers to implementing RA prevention.
  • To explore strategies and opportunities for RA prevention on local and global scales.

Main Methods:

  • Commentary synthesizing current knowledge on RA prevention.
  • Analysis of barriers across individual and healthcare system levels.
  • Discussion of potential benefits and drawbacks of RA prevention strategies.

Main Results:

  • Identified patient, provider, and healthcare system barriers impede RA prevention efforts.
  • Outlined strategies and opportunities to overcome these implementation challenges.
  • Acknowledged potential positive and negative consequences of RA prevention initiatives.

Conclusions:

  • Addressing multifaceted barriers is crucial for effective RA prevention.
  • Implementing targeted strategies can improve early identification and intervention for RA.
  • Careful consideration of individual and public health impacts is necessary for successful RA prevention programs.
Keywords:
access to carepreclinical diseasepreventionrheumatoid arthritis

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