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Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
Nephrotic syndrome without kidney injury revealing intravascular large B cell lymphoma
Lucie Pothen1, Selda Aydin2, Alessandra Camboni2
1Service de Médecine interne et Maladies Infectieuses, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium.
Abstract:
We describe the case of a 64-year-old woman admitted for fever of unknown origin, who developed nephrotic syndrome during hospitalisation and pulmonary infiltrates. Renal biopsy disclosed intracapillary glomerular invasion by intravascular large B cell lymphoma. Clinical and biological evolution was favourable after rituximab, cyclophosphamide, doxorubicine, vincristine and prednisone (R-CHOP) treatment and autologous stem cell transplant. Two years after diagnosis the patient was considered in remission.
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