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Does Rotavirus Vaccination Affect Longer-Term Intussusception Risk in US Infants?
Rachel M Burke1,2, Jacqueline E Tate1, Rebecca M Dahl3
1Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
None:
Rotavirus vaccination has been associated with a short-term increased risk of intussusception. Our analysis of insurance claims for 1 858 827 US children with 544 recorded cases of intussusception found a nonsignificant decrease in intussusception (hazard ratio, 0.79 [95% confidence interval, 0.57-1.09]) in fully rotavirus-vaccinated children followed up to the age of 2 years.
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