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Related Concept Videos

Review and Preview01:10

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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
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Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
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Histone Modification02:32

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
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Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
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Monomer Modifications of Denture Base Acrylic Resin: A Systematic Review and Meta-analysis.

R Ajay1, K Suma2, Seyed Asharaf Ali2

  • 1Department of Prosthodontics and Crown and Bridge, Vivekanandha Dental College for Women, Tiruchengode, Tamil Nadu, India.

Journal of Pharmacy & Bioallied Sciences
|June 15, 2019
PubMed
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Modified monomers can enhance denture base acrylic resin properties. Specifically, incorporating 20% methacrylic acid improved flexural strength, though further research on dimensional accuracy is needed.

Keywords:
Methyl-methacrylateMonomerbiocompatibilityproperties

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Area of Science:

  • Materials Science
  • Biomaterials Engineering
  • Polymer Chemistry

Background:

  • Methyl methacrylate (MMA) is a common denture base resin monomer.
  • Modifying MMA with other monomers aims to improve physico-mechanical properties and biocompatibility.
  • Optimal modification strategies for MMA monomers remain unclear.

Purpose of the Study:

  • To compare properties of conventional and modified denture base monomers.
  • To assess the impact of various factors on acrylic resin properties.
  • To synthesize findings from existing in vitro studies.

Main Methods:

  • Systematic review and meta-analysis following PRISMA guidelines.
  • Searched Ebscohost, PubMed, Semantic scholar, and J-stage databases (1995-2018).
  • Analyzed in vitro studies comparing modified and unmodified monomers using fixed-effect models.

Main Results:

  • High heterogeneity observed across all analyzed properties.
  • Monomers modified with 20% methacrylic acid demonstrated superior flexural strength.
  • Evidence suggests potential improvements in denture base resin properties with modified monomers.

Conclusions:

  • In vitro studies indicate modified monomers may enhance denture base resin properties.
  • High heterogeneity and risk of bias were noted in the included literature.
  • Dimensional accuracy requires further investigation as a key future research area.