Jove
Visualize
Contact Us

Related Concept Videos

Review and Preview01:10

Review and Preview

8.3K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.3K
Review and Preview01:13

Review and Preview

10.9K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
10.9K
Histone Modification02:32

Histone Modification

16.0K
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
16.0K
Histone Modification02:32

Histone Modification

4.4K
4.4K
Spreading of Chromatin Modifications02:25

Spreading of Chromatin Modifications

9.4K
The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
Writers
The writer...
9.4K
Behavior Modification01:21

Behavior Modification

589
Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them.
A real-world application of operant conditioning principles is applied...
589

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique on Primary and Secondary Implant Stability in Rabbit Model Split Body RCT.

The journal of contemporary dental practice·2025
Same author

Comparative Analysis of the Effects of Two Different Drill Designs on Insertion Torque and Primary Stability during Osteotomy - An <i>In Vivo</i> Animal Study.

Journal of pharmacy & bioallied sciences·2024
Same author

Chemical characterization of silanized silver nanoparticles impregnated in poly (methyl methacrylate) resin: An <i>in vitro</i> study.

Journal of Indian Prosthodontic Society·2023
Same author

Evaluation of the <i>In-Vitro</i> Cytotoxicity of Heat Cure Denture Base Resin Modified with Recycled PMMA-Based Denture Base Resin.

Journal of pharmacy & bioallied sciences·2022
Same author

Analysis of Surface Morphology and Elemental Composition on Zirconia Implants Before and After Photofunctionalization by Scanning Electron Microscopy and Energy Dispersive X ray Spectroscopy - An <i>In vitro</i> Study.

Journal of pharmacy & bioallied sciences·2021
Same author

Analysis of Surface Roughness and Three-dimensional Scanning Topography of Zirconia Implants before and after Photofunctionalization by Atomic Force Microscopy: An <i>In Vitro</i> Study.

Journal of pharmacy & bioallied sciences·2021
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 23, 2026

Multi-material Ceramic-Based Components &#8211; Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)
08:29

Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)

Published on: January 7, 2019

11.8K

Surface Modification Techniques for Zirconia-Based Bioceramics: A Review.

Suma Karthigeyan1, Arun Jaikumar Ravindran2, Ramesh T R Bhat2

  • 1Department of Prosthodontics, Rajah Mutiah Dental College, Madurai, Tamil Nadu, India.

Journal of Pharmacy & Bioallied Sciences
|June 15, 2019
PubMed
Summary

Zirconia is a promising material for implants due to its strength and compatibility with the body. This review examines how changing the surface of zirconia can improve how well it works in the body. Techniques like polishing, acid treatment, and laser modification are discussed. These changes can affect how cells interact with the implant. The review suggests that more research is needed to understand how these changes help the body accept the implant better. It also emphasizes the need for more studies in living systems to confirm these findings.

Keywords:
Biofunctionalizationelectrophoretic depositionlaser treatmentsandblastingselective infiltration etchingself-assemblyultraviolet treatmentyttria-tetragonal zirconia polycrystalbioceramics surface modificationzirconia implant techniquesbiocompatibility of implantstissue response to implants

Frequently Asked Questions

More Related Videos

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment
08:48

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment

Published on: November 9, 2015

8.6K
Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

25.7K

Related Experiment Videos

Last Updated: Jan 23, 2026

Multi-material Ceramic-Based Components &#8211; Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)
08:29

Multi-material Ceramic-Based Components – Additive Manufacturing of Black-and-white Zirconia Components by Thermoplastic 3D-Printing (CerAM - T3DP)

Published on: January 7, 2019

11.8K
Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment
08:48

Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment

Published on: November 9, 2015

8.6K
Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
12:31

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Published on: August 19, 2012

25.7K

Area of Science:

  • Bioceramics in biomedical engineering
  • Surface modification techniques in materials science
  • Implant biomaterials in orthopedic and dental research

Background:

Zirconia is increasingly considered for biomedical implants due to its mechanical strength and biocompatibility. It is currently used in hip and dental implants. However, the success of zirconia implants depends heavily on surface properties. Prior research has shown that surface modifications can influence cell behavior and tissue integration. No prior work had resolved how best to optimize these modifications. This gap motivated a review of existing techniques. That uncertainty drove the need to assess their efficacy in tissue response. It was already known that surface topography and chemistry affect implant performance. This review aims to synthesize current knowledge to guide future research.

Purpose Of The Study:

The aim of this review is to evaluate surface modification techniques for zirconia-based bioceramics. These techniques include polishing, sandblasting, acid etching, and others. The motivation stems from the need to improve implant performance. Zirconia’s success in implants relies on surface characteristics. This paper seeks to clarify how different methods impact biocompatibility. It also highlights the need for more in vitro and in vivo studies. The study focuses on identifying gaps in current research. The goal is to inform future directions in implant material development.

Main Methods:

The authors conducted a literature review of zirconia surface modification techniques. They analyzed methods like polishing, sandblasting, and acid etching. Biofunctionalization and coating were also included in the assessment. Laser treatment and ultraviolet light were among the techniques reviewed. The study did not introduce new methods but synthesized existing ones. It evaluated each method’s impact on surface properties and tissue response. The approach involved comparing outcomes across studies. The review aimed to identify trends and limitations in current research.

Main Results:

Polishing and sandblasting were found to alter surface roughness and hardness. Acid etching improved surface energy and wettability. Biofunctionalization enhanced cell adhesion and proliferation. Coating methods added bioactive layers to the zirconia surface. Laser treatment increased surface area and porosity. Ultraviolet light treatment modified surface chemistry. The strongest finding was the correlation between surface modification and tissue response. These results suggest that optimized surfaces improve implant integration.

Conclusions:

The authors propose that surface modification is key to zirconia’s success as an implant material. They emphasize the need for more in vitro and in vivo studies. The review suggests that current methods have potential but lack consistency. No prior work had resolved how to standardize these techniques. The authors propose that future research should focus on tissue regeneration processes. They suggest that a better understanding of tissue response is essential. The findings highlight the importance of controlled surface properties. The review concludes that further studies are necessary to validate these methods.

The main outcome is improved tissue response and implant integration through altered surface properties.

Acid etching increases surface energy and wettability, promoting better cell adhesion.

Biofunctionalization enhances cell adhesion and proliferation, crucial for successful implant integration.

Laser treatment increases surface area and porosity, potentially improving tissue interaction.

Ultraviolet light modifies surface chemistry, which may influence cell behavior and integration.

The authors propose more in vitro and in vivo studies to understand tissue regeneration processes.