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Updated: Jan 23, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Erythema multiforme major induced by sunitinib for metastatic renal cell carcinoma
Daisuke Watanabe1,2, Akemi Yamashita2, Tadaaki Minowa2
1Department of Palliative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Abstract:
There are currently several options for tyrosine kinase inhibitor as a systemic therapy for metastatic renal cell carcinoma (mRCC). The successful control of adverse events caused by such drugs, along with eliciting long-term maximum effect, are the major issues with respect to the treatment strategy for mRCC. We herein report the clinical course of mRCC, in which erythema multiforme major was observed on the 13th day of the first course of sunitinib, but the symptoms improved after the immediate withdrawal of sunitinib, as well as the administration of topical steroids and oral antihistamines alone.
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