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Updated: Jan 23, 2026
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Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults
Published on: December 9, 2014
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When clozapine appears at a dance event….
Lisbeth Patteet1, Kristof Maudens1, Sarah Wille2
1Toxicological Centre, University of Antwerp , Wilrijk, Belgium.
Acta Clinica Belgica
|June 15, 2019
Summary
Party drug users experienced clozapine intoxication due to misidentified tablets. Standard drug screens may miss this, necessitating specialized toxicology analysis for unusual intoxication cases.
Area of Science:
- Toxicology
- Emergency Medicine
- Pharmacology
Background:
- Party drugs often have unknown contents and variable dosages, increasing risks.
- Substance abuse at events poses diagnostic challenges for medical professionals.
Observation:
- Three individuals at a dance event presented with severe symptoms, including respiratory distress, bradycardia, syncope, and altered mental status.
- One patient required intubation due to breathing difficulties.
Findings:
- Blood tests confirmed clozapine intoxication, with serum concentrations below therapeutic ranges but indicative of recent intake.
- A pill identified as clozapine (Leponex® 100 mg) was found, suggesting it was sold as a party drug.
- Symptoms observed were consistent with clozapine's known side effects in naive individuals, even at low doses.
Implications:
- Routine toxicology screening may fail to identify clozapine as the causative agent.
- Unusual intoxication symptoms warrant advanced testing at a reference toxicology laboratory.
- This highlights the danger of misidentified substances in recreational drug use and the need for better screening protocols.
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