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Updated: Jan 23, 2026

Impression Cytology of the Lid Wiper Area
Published on: August 9, 2016
[Impressionable cytology method in diagnostics of dry eye syndrome.]
N M Zakharova1, I P Shabalova2, G H Ali-Zade3
1Serpukhov Town Hospital by N.A. Semashko, 142200, Moscow Region, Russian.
Abstract:
Analysis of the cellular composition of the eyeball conjunctival prints and evaluation of the informative of the cytomorphological method of research in the diagnosis of dry eye syndrome (DES). Cytological examination using impression cytology was performed in 72 patients: 60 patients with DES and 12 without eye disease (control group). The main component of cytological sample in patients with DES are (a) squamous epithelium (hyperkeratocytes); (b) groups and clusters of flattened epithelial cells; (c) a small amount (up to five in the preparation) of goblet cells. Impression cytology method improves the accuracy of diagnosis of DES.
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