Related Experiment Video
Updated: Jan 23, 2026

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
Published on: July 4, 2007
Genetic diversity of HLA system in two populations from Sinaloa, Mexico: Culiacán and rural Sinaloa
Stephen Clayton1, Rodrigo Barquera2, María Guadalupe Uribe-Duarte3
1Department of Archaeogenetics, Max Planck Institute for the Science of Human History (MPI-SHH), Jena, Germany.
Abstract:
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 286 Mexicans from the state of Sinaloa living in Culiacán (N = 103) and rural communities (N = 183) to obtain information regarding allelic and haplotypic frequencies. We find that the most frequent haplotypes for the state of Sinaloa include ten Native American most probable ancestry and five European most probable ancestry haplotypes. The admixture estimates revealed that the main genetic components in the state of Sinaloa are European (62.39 ± 3.47%) and Native American (37.61 ± 2.85%), while the African genetic component was estimated as virtually absent (0.00 ± 1.86%).
Related Concept Videos
What is Population Genetics?
Conservation of Small Populations
Genetics of Speciation
Population Growth
Diversity of Archaea I
Diversity of Archaea II

