Implant-based breast reconstruction with Artia™ tissue matrix

Area of Science:

• Plastic Surgery
• Biomaterials
• Breast Reconstruction

Background:

• Artia™ (porcine acellular dermal matrix) was introduced in 2015.
• Limited clinical data exists for Artia™ in breast reconstruction.
• This study addresses the need for clinical outcome data.

Purpose of the Study:

• To assess outcome data for Artia™-assisted breast reconstruction.
• To compare Artia™ outcomes with other non-human acellular dermal matrices (ADMs).

Main Methods:

• Prospective study of patients undergoing Artia™-assisted breast reconstruction (July 2016 - February 2018).
• Data collected included patient demographics, reconstruction type, implant details, oncological data, complications, and adjuvant treatment delays.
• Compared outcomes with literature data on other ADMs.

Main Results:

• 83 implant-based breast reconstructions in 51 patients using Artia™.
• Reconstructions included risk-reducing mastectomy (62%), therapeutic mastectomy (28%), and revisions (10%).
• Overall complication rate was 10.8% (seromas 7.2%, hematoma 1.2%, implant loss 2.4%) with a mean 276-day follow-up. No wound dehiscence or erythema/red breast syndrome.

Conclusions:

• Artia™-assisted implant-based breast reconstruction demonstrates low and acceptable early complication rates.
• Results are comparable to established ADMs.
• Artia™ shows potential as a safe and effective option for breast reconstruction.