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Updated: Jan 23, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
A case of mixed-pattern calcifications in multinodular goiter associated with a benign diagnosis
D Bianchi1, U Morandi1, A Stefani1
1Division of Thoracic Surgery, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena, Via Largo del Pozzo n. 71, 41124 Modena, Italy.
Background:
Calcified nodules are often found in a goiter when performing an ultrasound of the neck. An analysis of different calcification patterns could contribute to discriminating between nodules with a lower malignancy risk and those with a higher malignancy risk. In certain cases, the results of a simple cytological analysis of a nodule are not specific enough to be completely trusted.
Case Presentation:
We present the case of a goiter with a mixed calcification pattern, including a type of calcification that is strongly associated with a malignant diagnosis, for which a completely benign diagnosis was determined.
Conclusion:
We believe that further studies examining a combination of ultrasound (US) and computed tomography (CT) scan presentations of thyroid nodules need to be performed.
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