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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Diffusion tensor cardiovascular magnetic resonance.

Zohya Khalique1,2, Dudley Pennell3,2

  • 1CMR Unit, Royal Brompton Hospital, London, UK.

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|June 17, 2019
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Summary
This summary is machine-generated.

Diffusion tensor cardiovascular magnetic resonance (DT-CMR) non-invasively assesses cardiac microstructure. This novel technique reveals myocardial organization and aids in diagnosing heart conditions like cardiomyopathy and ischemic heart disease.

Keywords:
cardiac MRIdiffusion tensormicrostructure

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Area of Science:

  • Cardiovascular imaging
  • Cardiac MRI
  • Biomarkers

Background:

  • Cardiac structure and function are intricate.
  • Current in vivo methods offer macroscopic views of the heart.
  • Non-invasive assessment of cardiac microstructure is needed.

Purpose of the Study:

  • Introduce diffusion tensor cardiovascular magnetic resonance (DT-CMR) as a novel technique.
  • Highlight DT-CMR's ability to assess cardiac microstructure non-invasively.
  • Demonstrate DT-CMR's potential in diagnosing and prognosing cardiac diseases.

Main Methods:

  • Utilizing diffusion tensor cardiovascular magnetic resonance (DT-CMR).
  • Assessing the helical arrangement of cardiomyocytes and sheetlet dynamics.
  • Employing diffusion biomarkers to describe myocardial expansion and organization.

Main Results:

  • DT-CMR provides insights into cardiomyocyte arrangement and sheetlet rotation.
  • Diffusion biomarkers quantify myocardial organization.
  • Novel microstructural abnormalities identified in cardiomyopathy, ischemic, and congenital heart disease.

Conclusions:

  • DT-CMR offers a non-invasive window into cardiac microstructure.
  • The technique reveals insights into myocardial organization and dynamics.
  • DT-CMR shows promise for improved diagnostics and prognostication in various cardiac conditions.