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Published on: February 9, 2011
A subcutaneous infection mimicking necrotizing fasciitis due to Butyricimonas virosa
Laura De Donder1, Ortwin Uyttebroek2, Stijn Van Cleven2
1Ghent University, Ghent, Belgium.
Introduction:
Butyricimonas virosa is a Gram-negative rod who was first identified in rat faces in 2009. Since then only six human infections have been described in literature of which five bacteremia and one bone abscess. We report a clinical case of a subcutaneous infection mimicking necrotizing fasciitis due to B. virosa.
Patient And Methods:
A 78-year-old man was referred to our hospital because of a wound infection at the surgical site with suspicion of necrotizing fasciitis. Treatment consisted of immediate surgical exploration with obtainment of intra-operative specimens for microbiologic examination, 15 d of negative pressure wound therapy (NPWT) and antibiotic treatment with piperacillin-tazobactam (12 d) plus vancomycin (9 d).
Results:
Surgical exploration did not show necrotising fasciitis but a subcutaneous infection mimicking necrotising fasciitis. The results of the intra-operative specimens revealed the presence of B.virosa and Finegoldia magna. Cultures taken during the NPWT replacements became negative and the patient was able to leave the hospital after 18 d.
Conclusions:
Considering there was no necrotizing infection present it may have been possible to safely close the wound sooner. However, it is difficult to differentiate between an actual necrotizing fasciitis and a subcutaneous infection mimicking necrotizing fasciitis. Therefore further studies on effective assessment tools to diagnose necrotizing fasciitis, such as the (modified) laboratory risk indicator for necrotizing fasciitis (LRINEC) score and enhanced computed tomography (CT), could be helpful.
Insights
A rare Gram-negative bacterium, Butyricimonas virosa, caused a subcutaneous infection mimicking necrotizing fasciitis in a patient. Early diagnosis and treatment were crucial for recovery, highlighting the need for better diagnostic tools.
Area of Science:
- Infectious Diseases
- Microbiology
- Surgical Infections
Background:
- Butyricimonas virosa, a rare Gram-negative rod, was first identified in rats in 2009.
- Human infections with B. virosa are infrequent, with only six cases reported previously, primarily bacteremia and one bone abscess.
Observation:
- A 78-year-old male presented with a surgical site infection suspected to be necrotizing fasciitis.
- Surgical exploration revealed a subcutaneous infection, not necrotizing fasciitis, caused by B. virosa and Finegoldia magna.
Findings:
- The patient received negative pressure wound therapy (NPWT) and antibiotics (piperacillin-tazobactam and vancomycin).
- Microbiologic cultures became negative during NPWT, and the patient was discharged after 18 days.
Implications:
- Differentiating subcutaneous infections mimicking necrotizing fasciitis is challenging.
- Further research into diagnostic tools like the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score and CT imaging is needed.
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