Use of X-ray Diffraction Technique of Hair for Oral Cancer Detection: A Proposal

Techniques that contribute to early diagnosis of oral potentially malignant disorders (OPMDs) and oral squamous cell carcinoma (OSCC) till now followed are vital staining, light-based detection systems along with various histological, cytological, molecular and imaging techniques.¹ In spite of histopathological technique being the gold standard, diagnosis by taking random biopsies of both clinically normal and the suspected oral area is impractical, since various serious downsides are associated with it and are also not appropriate for repetitive sampling at multiple sites.² A screening test which is non-invasive, safe without exposing an individual to X-radiation and more consistent than any other current method is direly required.