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Updated: Jan 23, 2026

Covalent Binding of BMP-2 on Surfaces Using a Self-assembled Monolayer Approach
Published on: August 26, 2013
Covalently bound monolayer patterns obtained by plasma etching on glass surfaces
Stan B J Willems1, Laura M I Schijven2, Anton Bunschoten3
1Laboratory of BioNanoTechnology, Wageningen University and Research, Bornse Weilanden 9, 6708 WG Wageningen, The Netherlands. vittorio.saggiomo@wur.nl and Wetsus, European Centre of Excellence for Sustainable Water Technology, Oostergoweg 9, 8911 MA Leeuwarden, The Netherlands and Interventional Molecular Imaging, Department of Radiology, Leiden University and Medical Centre, 2300 RC Leiden, The Netherlands.
Abstract:
Micropatterns of β-cyclodextrin (β-CD) monolayers on glass are obtained by using a plasma etching approach with polydimethylsiloxane (PDMS) stamps. This simple and versatile approach provides a promising alternative to current techniques for creating patterns of covalently bound molecules. It is also possible to fabricate sub-10 μm sized features.
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