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Drastic promotion of guanine oxidation via electron transfer in Ψ-type DNA
Shunsuke Sakurai1, Mayu Esumi1, Makiko Tanaka1
1Department of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585, Japan. makiko.tanaka@uec.ac.jp.
Abstract:
We investigated the effects of a crowded environment on guanine oxidation in pyrene-modified oligonucleotides by photoinduced electron transfer. We observed drastic promotion of guanine oxidation in Ψ (psi; polymer- and salt-induced)-type DNA.
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