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Related Experiment Video

Updated: Jan 23, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

Why Should We Advocate Maternal Immunization?

Jim Boonyaratanakornkit¹, Helen Y Chu

¹From the Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington.

The Pediatric Infectious Disease Journal

|June 18, 2019

Summary

This summary is machine-generated.

Maternal vaccination protects mothers and newborns from infections during vulnerable periods. Recommended vaccines like influenza and Tdap boost passive immunity transfer to infants.

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Published on: December 21, 2021

Area of Science:

Immunology
Maternal and Child Health
Vaccinology

Background:

Pregnancy involves immune tolerance, increasing susceptibility to infections for both mother and fetus.
Neonates have a vulnerable period before developing their own adaptive immunity.
Passive antibody transfer from mother to neonate via placenta and breast milk offers crucial protection.

Purpose of the Study:

To review the role and benefits of maternal vaccination in protecting pregnant women, fetuses, and neonates.
To discuss the immunological basis for maternal vaccination strategies.
To highlight current recommendations and future directions in maternal immunization.

Main Methods:

Review of existing literature on maternal vaccination and passive immunity.
Analysis of immunological changes during pregnancy.
Examination of vaccine efficacy and safety data for pregnant populations.

Main Results:

Maternal vaccination effectively boosts antibody transfer to the fetus and neonate.
Recommended vaccines include inactivated influenza, diphtheria, tetanus toxoid, and acellular pertussis (Tdap).
Maternal immunization is a key strategy to bridge neonatal immunity gaps.

Conclusions:

Maternal vaccination is a safe and effective public health intervention.
It provides essential protection against serious infectious diseases for mother and child.
Ongoing research is exploring new maternal vaccine candidates for broader protection.