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Updated: Jan 23, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
Published on: April 7, 2017
Follicular Dendritic Cell Sarcoma or Not? A Series of 5 Diagnostically Challenging Cases
Nicolas Lopez-Hisijos1, Reeba Omman1, Stefan Pambuccian1
1Department of Pathology, Loyola University Medical Center, Maywood, IL, USA.
Abstract:
Imperfect or unusual presentation, morphology, or immunophenotype can make the diagnosis of follicular dendritic cell sarcoma (FDCS) very challenging. To illustrate this, we present 5 unique cases from the archives of our tertiary care academic medical center that presented a diagnostic challenge wherein FDCS was the top differential diagnostic possibility. The workup of these cases, including multiple expert consultations, highlights the importance of avoiding specific pitfalls in the diagnosis of FDCS.
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