Related Experiment Video

Updated: Jan 23, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

2.1K

Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial

Alberto Frutos Pérez-Surio1,2, Roberto Lozano Ortiz3, Alejandro Martínez Crespo1,4

  • 1Department of Clinical Pharmacy, University Clinical Hospital Lozano Blesa, Zaragoza, Spain.

JRSM Cardiovascular Disease
|June 18, 2019
PubMed

Insights

Elderly patients with atrial fibrillation face a high stroke risk. Careful management of risk factors is crucial for preventing stroke and bleeding events in this population.

Area of Science:

  • Cardiology
  • Geriatrics
  • Pharmacology

Background:

  • Atrial fibrillation (AF) is a prevalent cardiac arrhythmia linked to increased morbidity and mortality.
  • Effective pharmacotherapy is essential for managing stroke and bleeding risks in AF patients.
  • Institutionalized elderly individuals with AF require specific attention due to their complex health profiles.

Purpose of the Study:

  • To assess the risk of stroke and bleeding in institutionalized patients diagnosed with atrial fibrillation.
  • To evaluate current pharmacotherapy strategies for stroke prevention in this patient group.
  • To identify factors influencing treatment decisions regarding anticoagulation and antiplatelet therapy.

Main Methods:

  • Prospective study design involving institutionalized patients with atrial fibrillation.
  • Utilized CHA2DS2-VASc criteria for stroke risk assessment.
  • Employed the HAS-BLED scale to evaluate bleeding risk.
  • Included patients with or without existing stroke prevention treatments.

Main Results:

  • Fifty-three elderly patients (mean age 86.4 years) were included.
  • A significant proportion (69.8%) were appropriately anticoagulated.
  • Among untreated or inadequately treated patients, challenges included advanced age, high bleeding risk, and dementia, impacting intervention decisions.

Conclusions:

  • Elderly institutionalized patients with atrial fibrillation exhibit a high risk of stroke.
  • Controlling modifiable risk factors is paramount for improving outcomes.
  • Individualized treatment approaches are necessary, balancing stroke prevention with bleeding risk.
Abstract

Keywords:
Cardiovascular agentsatrial fibrillationstroketreatment adherence and compliance

More Related Videos

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.8K
Robotic Ablation of Atrial Fibrillation11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

20.1K

Related Concept Videos

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
11.7K
Amyloid Fibrils03:03

Amyloid Fibrils

6.4K
Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
190
Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
3.6K
Fibril-associated Collagen01:11

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
3.3K
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
3.1K