Acute ST-elevation myocardial infarction in a young patient with antiphospholipid syndrome

Area of Science:

• Cardiology
• Hematology
• Immunology

Background:

• Acute coronary syndrome (ACS) is uncommon in young individuals.
• Antiphospholipid syndrome (APS) is a rare cause of thrombotic events, particularly in younger populations.

Observation:

• A 26-year-old Hispanic male presented with ST-elevation myocardial infarction (STEMI).
• He underwent percutaneous transluminal coronary angioplasty (PTCA) but experienced stent thrombosis within 48 hours.
• A left apical thrombus developed subsequently.

Findings:

• Hypercoagulable state studies confirmed the diagnosis of antiphospholipid syndrome.
• This case establishes a rare association between ACS, stent thrombosis, and APS in a young patient.

Implications:

• Early diagnosis and management of APS are crucial in young patients presenting with thrombotic cardiovascular events.
• This case underscores the importance of considering APS in unexplained thrombotic events, even in the absence of typical risk factors.
• Further research into the mechanisms linking APS and early-onset cardiovascular disease is warranted.