Related Experiment Video
Updated: Jan 23, 2026

Three-Dimensional Printing of a Complex Aortic Anomaly
Published on: November 1, 2018
Diagnostic Value of Two-Dimensional plus Four-Dimensional Ultrasonography in Fetal Craniocerebral Anomalies
Yingjin Wang1, Xiaoyuan Chen1, Shujuan Zhong1
1Medical Ultrasound Centre, Northwest Women's and Children's Hospital, Xian 710061, P.R. China.
Background:
To assess the clinical value of two-dimensional (2D) plus four-dimensional (4D) ultrasonography in diagnosis of fetal craniocerebral anomalies.
Methods:
Retrospective analysis was performed on the sonographic features of 83 maternity patients admitted to Northwest Women's and Children's Hospital, Xian China from January 2013 to December 2017 diagnosed with suspected fetal anomalies of the brain and skull through 2D and 4D ultrasonography.
Results:
Fifty six patients were diagnosed with the anomalies by 2D ultrasonography only, 65 patients by 4D ultrasonography only, and 74 patients by 2D plus 4D ultrasonography.76 patients were confirmed to have fetal craniocerebral anomalies after birth or induced labor. Diagnostic accuracies of 2D ultrasound only, 4D ultra-sound only, and 2D plus 4D ultrasound were 68.67%, 81.93% and 95.18%, respectively (P<0.05). The accuracy of 2D plus 4D ultrasound was greater than those of 2D ultrasound only and 4D ultrasound only, and the accuracy of 4D ultrasound only was higher than that of 2D ultrasound only (P<0.05). The sensitivity of 2D plus 4D ultrasound was greater than those of 2D ultrasound only and 4D ultrasound only (P<0.05). The specificity of 2D plus 4D ultrasound was greater than those of 2D ultrasound only and 4D ultrasound only (P<0.05).
Conclusion:
Combined ultrasonography can better differentiate fetal craniocerebral anomalies, providing early and more accurate information for clinicians as well as maternity patients to make a decision. This clinical practice would be valuable for improving the quality of the newborn population.
More Related Videos
07:04A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
06:46Mouse Fetal Whole Intestine Culture System for Ex Vivo Manipulation of Signaling Pathways and Three-dimensional Live Imaging of Villus Development
Published on: September 4, 2014
Related Concept Videos
Dimensional Analysis
Conversion Factors and Dimensional Analysis
The unit...
Dimensional Analysis
In fluid mechanics, dimensional...
Dimensional Analysis
Dimensional analysis allows us to analyze and compare physical quantities on a...
Dimensional Analysis
Three-Dimensional Force System
Two-Dimensional Force System