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Updated: Jan 23, 2026

Isolating Intestinal Stem Cells from Adult Drosophila Midguts by FACS to Study Stem Cell Behavior During Aging
Published on: December 16, 2014
Save your gut save your age: The role of the microbiome in stem cell ageing
Yi Tan1, Zongke Wei2, Jiaoliu Chen1
1Obstetrics and gynecology department, Dongguan nancheng hospital, Dongguan, China.
Abstract:
The tremendous importance of microbiota in microbial homoeostasis, alterations in metabolism and both innate and adaptive immune systems has been well established. A growing body of evidence support that dysbiosis or compositional changes in gut microbiota is linked to the ageing of stem cells in terms of dysregulations of metabolism, aberrant activation of the immune system as well as promoting epigenetic instability of stem cell. In this concise review, we elucidate recent emerging topics on microbiotic alterations and underlying mechanisms in stem cell ageing.
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