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Updated: Jan 23, 2026

Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published on: January 5, 2021
Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry
Alexander O Chizhov1, Yury E Tsvetkov2, Nikolay E Nifantiev3
1N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, Leninskii Prosp., 47, 119991 Moscow, Russia. chizhov@ioc.ac.ru.
Abstract:
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them (cyclodextrins and their derivatives) are widely used in drug design, as food additives, in the construction of nanomaterials, etc. The peculiarities of the first- and second-order mass spectra of cyclic oligosaccharides (natural, synthetic and their derivatives and modifications: cyclodextrins, cycloglucans, cyclofructans, cyclooligoglucosamines, etc.) are discussed in this minireview.
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