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Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
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[Endoscopic lung volume reduction for emphysema].

H Mal1, V Bunel1, A Marceau2

  • 1Service de pneumologie B, hôpital Bichat, Assistance publique-Hôpitaux de Paris, 75018 Paris, France; Inserm UMR1152, université Paris7 Denis Diderot, 75018 Paris, France.

Revue Des Maladies Respiratoires
|June 19, 2019
PubMed
Summary
This summary is machine-generated.

Endoscopic lung volume reduction offers an alternative to surgery for advanced emphysema, aiming to decrease hyperinflation and improve breathing without major risks. This review assesses various endoscopic techniques for emphysema management.

Keywords:
BPCOBronchoscopieBronchoscopyCOPDEmphysemaEmphysèmeHyperinflationHyperinflation.Interventional pneumologyLung volume reductionPneumologie interventionnelleRéduction de volume pulmonaire

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Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Interventional Pulmonology

Background:

  • Lung hyperinflation is a key symptom in advanced emphysema, causing significant breathing difficulties during exertion.
  • Surgical lung volume reduction is effective but carries high risks of morbidity and mortality.
  • Endoscopic lung volume reduction (ELVR) aims to reduce hyperinflation with lower risks.

Purpose of the Study:

  • To review the efficacy and safety of various endoscopic lung volume reduction techniques.
  • To present functional benefits and side effects based on high-quality controlled studies.
  • To propose an algorithm for the endoscopic management of advanced emphysema.

Main Methods:

  • Review of high-quality controlled studies on endoscopic lung volume reduction techniques.
  • Assessment of techniques including airway bypass, intrabronchial valves, coils, and vapor ablation.
  • Evaluation of functional outcomes and adverse events associated with each method.

Main Results:

  • Various endoscopic techniques have been evaluated for their effectiveness in reducing lung hyperinflation.
  • Data on functional improvements and potential side effects are presented for each method.
  • The review synthesizes findings to guide clinical decision-making.

Conclusions:

  • Endoscopic lung volume reduction provides a less invasive option for managing advanced emphysema.
  • The choice of technique depends on patient-specific factors and desired outcomes.
  • An algorithm is proposed to aid in the selection and application of ELVR strategies.