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Updated: Jan 23, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
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Lipid droplet-membrane contact sites - from protein binding to function

Abdou Rachid Thiam1, Isabelle Dugail2

  • 1Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris-Diderot, Sorbonne Paris Cité, 75005 Paris, France isabelle.dugail@inserm.fr thiam@ens.fr.

Journal of Cell Science
|June 19, 2019
PubMed
Summary

Lipid droplets (LDs) are evolving from simple fat storage sites to key players in cellular stress responses. Understanding how proteins interact with LDs and their connections to other organelles reveals their complex functions.

Keywords:
Contact sitesLipid dropletLipid metabolismMolecular tethersMultifunctional lipid dropletsProtein targeting

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