Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Catalysis

Catalysis

The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.

Atomic Structure

Atomic Structure

Atomic Mass

Atomic Mass

Atoms — and the protons, neutrons, and electrons that compose them — are extremely small. For example, a carbon atom weighs less than 2 × 10−23 g. When describing the properties of tiny objects such as atoms, we use appropriately small units of measure, such as the atomic mass unit (amu). The amu was originally defined based on hydrogen, the lightest element, then later in terms of oxygen. Since 1961, it has been defined with regard to the most abundant isotope of carbon, atoms of which...

Atomic Orbitals

Atomic Orbitals

An atomic orbital represents the three-dimensional regions in an atom where an electron has the highest probability to reside. The radial distribution function indicates the total probability of finding an electron within the thin shell at a distance r from the nucleus. The atomic orbitals have distinct shapes which are determined by l, the angular momentum quantum number. The orbitals are often drawn with a boundary surface, enclosing densest regions of the cloud.

Introduction to Mechanisms of Enzyme Catalysis

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...

Hybridization of Atomic Orbitals I

Hybridization of Atomic Orbitals I

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bioinspired Zr-Cu Dual Sites Regulate Hydrogen Peroxide Heterolysis for Naked-Eye Glyphosate Sensing.

ACS sensors·2026

Same author

Bi-Doped Pd Aerogels with Tensile-Strain-Induced Cascade Orbital Hybridization Boost H<sub>2</sub>O<sub>2</sub> Selective Activation for Efficient Pesticide Distinction.

Research (Washington, D.C.)·2026

Same author

Regulating the Adsorbed Hydrogen Coverage for a Good Trade-Off between Hydrogen Evolution Activity and Electrochemiluminescence Performance.

Analytical chemistry·2026

Same author

Toward Bioreceptor-Free Nanozyme Sensing: Matched Interaction and Ligand-Modulated Phosphatase-Mimetic Activity Enable Anti-Interference and Sensitive Detection of Quinolones in Dairy Products.

Analytical chemistry·2026

Same author

Correction to "Single-Atom Ce-Doped Metal Hydrides with High Phosphatase-like Activity Amplify Oxidative Stress-Induced Tumor Apoptosis".

ACS nano·2026

Same author

Reactive Hydrogen-Mediated Peroxydisulfate Activation for Boosting Carbon Nitride Electrochemiluminescence.

Analytical chemistry·2026

Search research articles

Related Experiment Video

Updated: Jan 23, 2026

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Published on: February 28, 2019

When Nanozymes Meet Single-Atom Catalysis.

Lei Jiao¹, Hongye Yan¹, Yu Wu¹

¹Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan, 430079, P.R. China.

Angewandte Chemie (International Ed. in English)

|June 19, 2019

Summary

This summary is machine-generated.

Single-atom nanozymes combine nanozymes and single-atom catalysts for enhanced applications. This review covers their synthesis, characterization, and use in sensing, pollutant degradation, and therapeutics.

Keywords:

SAzymes biosensors nanozymes organic pollutant degradation therapeutic drugs

More Related Videos

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Published on: February 27, 2015

Related Experiment Videos

Last Updated: Jan 23, 2026

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Published on: February 28, 2019

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

Published on: February 27, 2015

Area of Science:

Materials Science
Catalysis
Nanotechnology

Background:

Nanozymes offer cost-effective, stable alternatives to natural enzymes.
Single-atom catalysts (SACs) provide atomically dispersed active sites, mimicking metalloproteases.
SACs bridge the gap between natural enzymes and nanozymes.

Purpose of the Study:

To review the properties, synthesis, and characterization of nanozymes and SACs.
To highlight advances in single-atom nanozymes.
To discuss applications and future challenges.

Main Methods:

Literature review of nanozymes and SACs.
Analysis of synthesis and characterization techniques.
Exploration of application data.

Main Results:

Single-atom nanozymes exhibit unique properties and significant potential.
Advances in synthesis and characterization enable precise control.
Promising applications in sensing, environmental remediation, and therapy.

Conclusions:

Single-atom nanozymes represent a significant advancement in catalysis.
Further research is needed to overcome challenges and unlock full potential.
Integration of nanozymes and SACs offers exciting opportunities.