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Published on: October 22, 2014
Suboptimal cardiovascular risk management in rheumatoid arthritis patients despite an explicit cardiovascular risk
M Heslinga1, Iam Van Den Oever1, D L Jonker2
1Amsterdam Rheumatology and Immunology Center/Reade , Amsterdam , The Netherlands.
Insights
Cardiovascular risk screening in rheumatoid arthritis (RA) patients identified high-risk individuals. Despite clear guidelines, preventive treatment initiation and lifestyle changes remain challenging for these high-risk RA patients.
Area of Science:
- Cardiology
- Rheumatology
- Public Health
Background:
- Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) risk.
- Early identification and management of CV risk factors are crucial for RA patients.
Purpose of the Study:
- To assess the initiation of preventive treatment and changes in CV risk scores 1 year after implementing a CV risk screening program for high-risk RA patients.
- To evaluate the effectiveness of targeted advice and referral in improving CV risk management in RA.
Main Methods:
- CV risk screening was conducted in a rheumatology clinic and general hospital.
- Patients identified as high CV risk received targeted advice for preventive drug initiation or adjustment.
- CV risk, lifestyle, and treatment were reassessed after 1 year; patients with prior CV disease were excluded.
Main Results:
- 58% of RA patients had a high 10-year CV risk (>20%), with 55% indicated for antihypertensives or statins.
- Only one-third of patients with an indication for preventive drugs started or adjusted treatment.
- 42% of patients reported lifestyle changes, including increased exercise, diet modification, and weight loss.
Conclusions:
- Implementing CV risk screening and providing targeted advice in RA patients is essential but challenging.
- Primary prevention of CV disease in high-risk RA patients requires further improvement despite established guidelines.
- Active screening programs need to be optimized to ensure adequate uptake of indicated preventive treatments and lifestyle modifications.
Abstract:
Objective: In 2011, we started to offer cardiovascular (CV) risk screening to rheumatoid arthritis (RA) patients with a high CV risk. After 1 year, we assessed whether patients labelled as high CV risk had started preventive treatment when indicated, and whether the CV risk score had changed. Methods: CV risk screening was performed in both a large outpatient rheumatology clinic and a general hospital in the Netherlands, and the general practitioner or the internist was informed about the results of the CV screening, including specific advice on the initiation or adjustment of cardiopreventive drugs. National guidelines were used to assess how many patients were eligible for preventive treatment. After 1 year, CV risk, lifestyle, and treatment were re-evaluated. Patients with a history of CV disease at baseline or who experienced a CV event during follow-up were excluded from the analyses. Results: A high 10 year CV risk (> 20%) was present in 58%, and 55% had an indication for anti-hypertensives, statins, or both. At follow-up, cardiopreventive drug treatment had been started or adjusted in only one-third of patients with an indication for treatment. After screening, 42% of patients reported having changed their lifestyle, through more exercise (24%), diet adaption (20%), and weight loss (11%). Conclusion: Despite clear guidelines to improve CV risk, the results of a programme comprising active screening, targeted advice, and referral to the general practitioner or internist prove that primary prevention remains a major challenge in high-risk RA patients.
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