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Evaluation of choroidal changes in adolescent idiopathic scoliosis using enhanced depth imaging optical coherence
Döndü Melek Ulusoy1, Serkan Akkaya1, Sabri Batın2
1Department of Ophthalmology, Kayseri Training and Research Hospital, Kayseri, Turkey.
Background:
We aimed to evaluate the choroidal thickness (CT) in patients with adolescent idiopathic scoliosis (AIS) using enhanced depth imaging optical coherence tomography (EDI-OCT).
Methods:
In this cross-sectional, observational comparative study, 56 eyes of 56 patients with AIS and 56 eyes of 56 age- and sex-matched healthy subjects were included. All participants underwent complete ophthalmologic examination and CT measurements at the fovea and at 750 μm intervals from the fovea to 1,500 μm in the nasal and temporal site obtained by spectral domain EDI-OCT.
Results:
The mean subfoveal CT was lower in the AIS patients (285.2 ± 24.4 μm) than that of the controls (313.2 ± 28.8 μm; p < 0.001). The difference was also significant at all extrafoveal measurement points (p < 0.001 for all). There were negative correlations of CTs at subfoveal and extrafoveal locations with the Cobb's angle in the AIS patients (for subfoveal location: r = -0.71 and p < 0.001; and for extrafoveal locations: r = -0.66 and p < 0.001 at 750 μm in the nasal side; r = -0.64 and p < 0.001 at 1,500 μm in the nasal side; r = -0.71 and p < 0.001 at 750 μm in the temporal side; and r = -0.69 and p < 0.001 at 1,500 μm in the temporal side).
Conclusion:
This preliminary study showed that AIS patients have thinner CT compared to that of healthy subjects. The lower CT was correlated with the increased angle of scoliosis.
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