Elastography for the evaluation of thyroid nodules in pediatric patients
Gustavo Bittar Cunha1, Luciana Cristante Izar Marino1, André Yamaya1
1Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Insights
Elastography, a non-invasive imaging technique, shows promise in evaluating pediatric thyroid nodules. High elasticity suggests a low cancer risk, potentially reducing unnecessary surgeries for children and adolescents.
Area of Science:
- Pediatric Endocrinology
- Diagnostic Imaging
- Oncology
Background:
- Thyroid nodules are common in children and adolescents.
- Accurate diagnosis is crucial to differentiate benign from malignant lesions.
- Elastography offers a non-invasive method to assess tissue stiffness.
Purpose of the Study:
- To assess the utility of manual compression elastography as an adjunct diagnostic tool for pediatric thyroid nodules.
- To correlate elastography findings with histopathological diagnoses.
Main Methods:
- Prospective study involving 32 pediatric patients (6-18 years) with 38 thyroid nodules.
- Elastography, ultrasound, and fine-needle aspiration biopsy were performed.
- Elastography findings were compared to histopathology.
Main Results:
- Elastography findings correlated with histopathology in 78.5% of cases.
- High elasticity was observed in only one malignant nodule, suggesting a low risk.
- Prioritizing elastography could have prevented three unnecessary thyroidectomies.
Conclusions:
- High elasticity on elastography indicates a low risk of malignancy in pediatric thyroid nodules.
- Elastography may serve as a valuable complementary screening tool for pediatric thyroid nodules.
- Further studies are needed to confirm these findings.
Objective:
To evaluate the usefulness of elastography (using manual compression) as an additional diagnostic tool for children and adolescents with thyroid nodules.
Materials And Methods:
This was a prospective study conducted between September 2012 and August 2013 at a hospital in Brazil. We performed elastography, ultrasound, and fine-needle aspiration biopsy in 32 patients between 6 and 18 years of age who had, in total, 38 thyroid nodules.
Results:
The elastography findings correlated with the histopathological diagnosis in 78.5% of cases. In three patients, an unnecessary thyroidectomy could have been avoided if the elastography results had been prioritized. Only one malignant thyroid nodule was found to show high elasticity.
Conclusion:
Our results suggest that high elasticity of a nodule on elastography is associated with a low risk of thyroid cancer. If further confirmed in other studies, elastography may prove useful as a complementary test for screening thyroid nodules in children.
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