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Relationship between VITAMIN D and chronic periodontitis
Amitesh Bhargava1, Pavitra Rastogi1, Nand Lal1
1Department of Periodontology, King George Medical University, Lucknow, India.
Journal of Oral Biology and Craniofacial Research
|June 19, 2019
Summary
Vitamin D deficiency is linked to chronic periodontitis, impacting gum health and bone loss. Lower vitamin D levels correlate with increased gingival index, pocket depth, and attachment loss in periodontitis patients.
Area of Science:
- Periodontology
- Endocrinology
- Immunology
Background:
- Chronic periodontitis involves plaque bacteria, host immune response, and periodontal tissue destruction.
- Vitamin D is crucial for bone health and immune function.
- Vitamin D deficiency may negatively impact the periodontium.
Purpose of the Study:
- To investigate the relationship between chronic periodontitis and vitamin D levels.
- To correlate periodontal clinical parameters with serum vitamin D concentrations.
Main Methods:
- A clinico-biochemical study involving 168 subjects with chronic periodontitis.
- Assessment of Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL).
- Correlation of these parameters with serum 25-hydroxyvitamin D [25(OH) D] levels.
Main Results:
- A statistically significant relationship was found between serum 25(OH) D levels and GI, PPD, and CAL.
- No significant relationship was observed between serum 25(OH) D levels and PI.
- Patients with chronic periodontitis generally exhibited low serum vitamin D levels, though severity did not correlate with vitamin D levels.
Conclusions:
- Serum 25(OH) D levels are significantly related to key periodontal parameters (GI, PPD, CAL).
- Vitamin D status is a relevant factor in chronic periodontitis.
- Further research may explore vitamin D supplementation's role in periodontitis management.
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