Related Experiment Video
Updated: Jan 23, 2026

10:32
Surgical Tips and Tricks for Performing Porcine Pancreas Transplantation
Published on: July 20, 2022
2.5K
(Technically) Difficult colonoscope insertion - Tips and tricks
Eduardo Rodrigues-Pinto1, Joel Ferreira-Silva1, Guilherme Macedo1
1Gastroenterology Department, Centro Hospitalar São João, Porto, Portugal.
Summary
Achieving cecal intubation is key for complete colonoscopy. Strategies for difficult colonoscopies, addressing patient and endoscopist factors, improve success rates and ensure thorough lesion detection.
Area of Science:
- Gastroenterology
- Endoscopy
- Medical Procedures
Background:
- Cecal intubation is essential for a complete colonoscopy.
- Difficult colonoscopies, defined by challenges in reaching the cecum, are common.
- Incomplete colonoscopies risk missing significant lesions.
Purpose of the Study:
- To outline strategies for achieving successful cecal intubation.
- To address the common issue of difficult colonoscopies.
- To emphasize the importance of complete colon examination.
Main Methods:
- Characterizing difficulties as redundant colon or sigmoid colon issues.
- Employing varied endoscopic techniques and equipment.
- Allocating sufficient time for the procedure.
Main Results:
- Most patients with prior incomplete colonoscopies can be successfully intubated.
- Careful attention to technique, scope choice, and methods enhances success.
- Problem characterization guides the approach to difficult cases.
Conclusions:
- Successful cecal intubation is achievable even in difficult cases.
- A systematic approach tailored to the cause of difficulty is crucial.
- Complete colonoscopy prevents missed pathologies and improves patient care.
Related Concept Videos
Porin Insertion in the Outer Mitochondrial Membrane
4.7K
Porins are beta-barrel proteins translocated to the mitochondrial outer membrane through the TOM complex into the intermembrane space. Porin precursors bind TIM chaperones within the intermembrane space and are guided to the Sorting and Assembly Machinery complex or SAM complex on the outer mitochondrial membrane.
Three models describe the assembly of porins by the SAM complex and their insertion into the outer membrane. Model 1 suggests that porins are assembled outside the SAM channel as the...
Three models describe the assembly of porins by the SAM complex and their insertion into the outer membrane. Model 1 suggests that porins are assembled outside the SAM channel as the...
4.7K
Insertion of Single-pass Transmembrane Proteins in the RER
16.9K
Integral membrane proteins are proteins adhered to the lipid bilayer of a cell organelle or membrane. They can be of two types: transmembrane integral proteins that span the lipid bilayer and monotopic proteins that are attached to either side of the membrane but do not pass through it.
Integral transmembrane proteins possess transmembrane and extra membrane domains. The transmembrane domains are primarily made of 20-25 hydrophobic amino acids arranged in a helical secondary confirmation. These...
Integral transmembrane proteins possess transmembrane and extra membrane domains. The transmembrane domains are primarily made of 20-25 hydrophobic amino acids arranged in a helical secondary confirmation. These...
16.9K
Insertion of Multi-pass Transmembrane Proteins in the RER
17.9K
The rough ER membrane synthesizes, assembles, and embeds transmembrane proteins in diverse topologies. These proteins function as transporters or channels and can remain in the ER membrane or are sent to the Golgi complex, lysosome, and cell membrane.
The multipass transmembrane proteins are the type IV integral membrane proteins with multiple topogenic sequences determining their spatial arrangement in the ER membrane. Nearly all multipass proteins lack a cleavable signal sequence and use...
The multipass transmembrane proteins are the type IV integral membrane proteins with multiple topogenic sequences determining their spatial arrangement in the ER membrane. Nearly all multipass proteins lack a cleavable signal sequence and use...
17.9K
RNA Editing
9.8K
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
9.8K
Surveys
16.7K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
16.7K
Nuclear Fusion
33.7K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.7K

