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Published on: September 22, 2017
Predicting postoperative atrial fibrillation after myocardial revascularization without cardiopulmonary bypass: A
Edgar Vidotti1, Lisia F K Vidotti1, Camila A G Arruda Tavares1
1Hospital Norte Paranaense, Arapongas, Paraná, Brazil.
Insights
Off-pump coronary artery bypass grafting (CABG) has a low incidence of postoperative atrial fibrillation (POAF). Chronic renal failure and exclusive use of venous grafts are key predictors of POAF in these patients.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Arrhythmia Research
Background:
- Postoperative atrial fibrillation (POAF) is a significant concern following coronary artery bypass grafting (CABG).
- Off-pump CABG (OPCABG) may offer potential benefits in reducing POAF incidence.
- Understanding POAF predictors in OPCABG is crucial for patient management.
Purpose of the Study:
- To determine the incidence of POAF in patients undergoing CABG without cardiopulmonary bypass (CPB).
- To identify independent predictor factors for POAF in the context of OPCABG.
Main Methods:
- Retrospective cohort study of 280 patients undergoing OPCABG from December 2008 to December 2011.
- Evaluation of patient characteristics, comorbidities (including chronic renal failure), and graft types (arterial vs. venous).
- Statistical analysis using univariate and multivariate models to identify POAF predictors.
Main Results:
- The overall incidence of POAF after OPCABG was 5.0%.
- Chronic renal failure (CRF) was independently associated with an increased risk of POAF (OR, 3.31).
- Exclusive use of venous-origin grafts also significantly increased POAF risk (OR, 9.81).
Conclusions:
- Off-pump CABG is a safe and effective myocardial revascularization technique with a low POAF rate.
- Chronic renal insufficiency is an independent risk factor for POAF after OPCABG.
- The sole use of venous grafts is a significant predictor of POAF in OPCABG patients.
Introduction:
Considering the threat imposed by postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG) and the potential benefits of off-pump CABG, the objective of this study was to describe the incidence and identify predictor factors for POAF in patients undergoing CABG without cardiopulmonary bypass (CPB).
Methods:
In this retrospective cohort study, we enrolled patients undergoing CABG without CPB between December 2008 and December 2011. The independent variables evaluated in this study were major patients' characteristics (age, sex, and ethnia), associated comorbidities (systemic arterial hypertension, diabetes mellitus, thyroid dysfunction, chronic renal failure (CRF), chronic obstructive pulmonary disease, and ischemic stroke), and the revascularization approach (the number of grafts used, the revascularized branch, and the choice of vascular graft (arterial or venous). The dependent variable was the onset of atrial fibrillation after the procedure.
Results:
Two hundred and eighty patients were included in the present study. The overall incidence of POAF after off-pump CABG was 5.0%. In the univariate analysis, the presence of chronic renal failure (odds ratio [OR], 3.01 [1.00-9.06], P = .049) and the use of venous-origin graft alone (OR, 9.67 [1.15-81.56], P = .037) were associated with an increased risk or POAF. These findings were confirmed after multivariate analysis, for both CRF (OR, 3.31 [1.05-10.46], P = .042) and the use of venous-origin graft alone (OR, 9.81 [1.13-85.35], P = .039).
Conclusion:
Off-pump coronary artery bypass grafting proved a safe and effective procedure, with low postoperative atrial fibrillation occurrence, for myocardial revascularization. Chronic renal insufficiency and the use of venous-origin graft solely proved to be independent predictor factors for PAOF.
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